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Hot off the press! Schisler Lab Paper news!

2022-06-20

Co-authors Selin Altinok and Jonathan Schisler participated in the formal analysis and investigation on:

The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP

 

Co-authors Rebekah Sanchez-Hodge, Selin Altinok, Leah Oswalt, and Dr. Jonathan Schisler worked with collaborators in the Netherlands on this Nature Communications cancer piece:

Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling

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2022 Human Research Program Investigators’ Workshop

2022-01-19

Are you interested in learning more about the Schisler Lab and operations in space? Register for the 2022 Human Research Program Investigators’ Workshop on 2/07-2/10. This workshop aims to provide an informal, collegial atmosphere for cross-disciplinary interaction. Click on the graphic below to sign up; we hope to see you there!

New review published by Schisler Lab members

2021-11-22

Congratulations to Selin Altinok, Becky Sanchez, Jonathan Schisler, Mariah Stewart, and Kaitlan Smith for their newly published review!

Learn more about “Co-Chaperones Mediate Health and Disease by Modifying Chaperone Function and Protein Triage” here:

Click on graphic to learn more!

Congratulations to the Class of 2020 Schisler Lab Alumni!

2021-11-03

We celebrate our past & present lab members every day, but this week especially our Class of 2020! UNC held their long awaited graduation ceremony on Oct. 9-10 and we are incredibly proud of all of you! The Schisler Lab Class of 2020 brought creativity, discovery, and laughs to the table making our research space that much better.

In order:
(1) Ellie Wilson is a Biomedical Engineering grad student @ Temple University
Alex Eaker is a Research Tech in the Baldwin Lab @ UNC Neuro
(2) Sarah Chiavacci (middle) is in a Physiology Master’s program and a doula
(3) Bridget Tarnowski is a Research Tech @ Merck Research Labs
(4) Charlie Roethling is a medical student @ UNC School of Medicine

Not pictured: Braxton Diekhoff (Pfizer) and Maddy Kennedy (UNC Hospitals)

Featured on the covers of Cell and Cell Reports- more news press on recent publications on Space Biology

2021-04-20

Both papers featuring the Schisler Lab landed on the cover with pictures from the ISS taken by Scott Kelly (one of the twins from the twin study, whose data we used in these papers)!

They got some nice press too:

https://www.nasa.gov/feature/ames/mitochondria-cell-science

https://www.cnn.com/2020/11/25/health/biology-of-spaceflight-studies-wellness-scn-trnd/index.html

https://www.popsci.com/story/science/spaceflight-human-body-effects/

 

Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.

PMID: 33242417

da Silveira WA, Fazelinia H, Rosenthal SB, Laiakis EC, Kim MS, Meydan C, Kidane Y, Rathi KS, Smith SM, Stear B, Ying Y, Zhang Y, Foox J, Zanello S, Crucian B, Wang D, Nugent A, Costa HA, Zwart SR, Schrepfer S, Elworth RAL, Sapoval N, Treangen T, MacKay M, Gokhale NS, Horner SM, Singh LN, Wallace DC, Willey JS, †Schisler JC, Meller R, McDonald JT, Fisch KM, Hardiman G, Taylor D, Mason CE, Costes SV, Beheshti A. Cell. 2020 Nov 25;183(5):1185-1201.e20. doi: 10.1016/j.cell.2020.11.002. PMID: 33242417

 

 

 

 

 

Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.

PMID: 33242410

Malkani S, Chin CR, Cekanaviciute E, Mortreux M, Okinula H, Tarbier M, Schreurs AS, Shirazi-Fard Y, Tahimic CGT, Rodriguez DN, Sexton BS, Butler D, Verma A, Bezdan D, Durmaz C, MacKay M, Melnick A, Meydan C, Li S, Garrett-Bakelman F, Fromm B, Afshinnekoo E, Langhorst BW, Dimalanta ET, Cheng-Campbell M, Blaber E, Schisler JC, Vanderburg C, Friedländer MR, McDonald JT, Costes SV, Rutkove S, Grabham P, Mason CE, Beheshti A. Cell Rep. 2020 Nov 21:108448. doi: 10.1016/j.celrep.2020.108448. Online ahead of print. PMID: 33242410