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Our Research

The Schisler Lab focuses on understanding the contribution of aging and our personal genome in complex diseases.
Our expertise lies in integration of complex genomic-biologic data to elucidate risk relationships in both murine and human systems with a focus on human diseases.

Explore our laboratory!


Meet the Lab Publications Donate

The Schisler Lab welcomes new rotation student, Jacob Pantazis

The Brown and Schisler lab put out a call for rotation students who want a unique co-mentoring opportunity, and Jacob was the first to answer. I had the chance to interview Jacob for his interview into our BBSP program, and … Continued

Opening the door for CHIP pharmacology

A new study published from a great collaboration with David Kass, Mark Ranek, and the Hopkins crew is now out at Nature Communications; read and share! Strong work by Becky Sanchez, Cornelia Virus, and Team CHIP.  

MiniMUGA paper published

We were happy to contribute to a genetics study to improve rigor and reproducibility in mouse research. Even in our preclinical models of SCAR16/SCA48, we see clear impacts on the severity of phenotypes based on mouse strain. https://www.genetics.org/content/early/2020/10/16/genetics.120.303596

Kaitlan featured in Department of Pharmacology video on our community

Great Department and research family here in PHCO. Thanks for your insight, Kaitlan!

Read about how COVID-19 impacted our lab and our efforts to keep science happening safely!

A story in The Daily Tar Heel featuring lots of MHI faculty and our own Arjun Putcha! We are lucky to have great undergraduate researchers that make up a big part of our success. We may be limited in our … Continued

COVID-19 collaborative research in the Schisler Lab

Read more about COV-IRT, some of our work on COVID-19, and join us in helping the world understand and develop treatments for COVID-19. A great write-up by Alyssa LaFaro. Check it out!! UNC and NASA Study COVID-19, Protein Correlation

Meet our PhD students!

Setting the bar! Selin is a PhD candidate in the Pharmacology program and she is studying how the multi-functional enzyme CHIP regulates microtubule dynamics, including in models of neurodegeneration. I met Selin while teaching PHCO 732, our grant writing course … Continued

New grant! Big news from the Schisler Lab

We are thrilled to announce a new five year grant to study and develop treatments for diseases that involve proteins important to a process known as protein quality control. Click and read more on Vital Signs!

Latest research @ UNC IVB/MHI Symposium

Becky along with Sarah and Christina presented updates on the latest cardiovascular research projects going on in the lab. It was a great day of science, and little did we know it would be our last non-virtual gathering of the … Continued

The Head and the Heart

Great article featuring our ongoing collaboration with the Cohen lab! We are combining forces to biochemically modify the Tau protein, allowing us to understand how Tau functions, both in health and disease, so we can find better ways to treat … Continued